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Table 1 Characteristics of participants included in the analysis (n = 537)

From: Rheumatic disease patient decision-making about COVID-19 vaccination: a qualitative analysis

Characteristic

Mean ± SD or Frequency (%)

Age (years)

64.4 ± 11.9

 ≥ 65 years old

288 (53.6)

Female

468 (87.2)

White

503 (93.6)

Education (years)

15.3 ± 2.2

Rural residence

116 (21.7)

United States resident

503 (93.7)

Primary diagnosisa

Rheumatoid arthritis

291 (56.6)

Dupuytren’s

90 (17.5)

Osteoarthritis

43 (8.4)

Systemic lupus erythematosus

22 (4.3)

Fibromyalgia

24 (4.7)

Psoriatic arthritis

14 (2.7)

Ankylosing spondylitis

5 (1.0)

Other

25 (4.9)

Comorbid conditionsb

History of cancer

156 (33.3)

History of pulmonary disorder

251 (53.6)

History of heart disease

204 (43.6)

Disease activity

 

Pain Visual Analog Score (0–10)

4.0 ± 2.8

Patient global Visual Analog Score (0–10)

3.5 ± 2.4

HAQ-II (0–3)g

0.7 ± 0.6

Medicationsc

 

Any conventional synthetic DMARDg

219 (49.8)

Methotrexate

132 (30.0)

Leflunomide

29 (6.6)

Sulfasalazine

18 (4.1)

Mycophenolate

4 (0.9)

Cyclophosphamide

1 (0.2)

Any biologic DMARDg

174 (39.5)

Rituximab

17 (3.9)

Janus kinase inhibitor

18 (4.1)

Glucocorticoid

90 (20.5)

COVID-19g vaccine intentions

 

Not intending to get vaccinated/undecided

36 (6.7)

Vaccinated/intending to get vaccinated

531 (93.3)

Peri-vaccine DMARDg management

 

No medication changesd

387 (77.6)

Medication changed at direction of physiciand

72 (14.4)

Medication changed by patientd

57 (11.4)

Vaccine decision factors/attitudes

 

COVID-19g positive (currently or in the past)e

81 (15.1)

Frustrations with vaccine access

33 (6.1)

Reported COVID-19g vaccine side effectsd

411 (76.5)

Expressed any concerns about vaccinef

447 (83.2)

Concerns about side effects

384 (71.5)

Concerns about DMARDg management/flares

105 (19.6)

Concerns about effectiveness

27 (5.0)

Mistrust/vaccine not needed

20 (3.7)

  1. aDiagnosis was available for n = 514
  2. bComorbidity information was available for n = 468
  3. cMedication information was available for n = 440
  4. dAmong those vaccinated (n = 499). Medication could be changed by patient, physician, both, or neither
  5. eEver reported COVID-19 diagnosis to FORWARD on previous questionnaires
  6. fIt was possible for individual commenters to be concerned about multiple aspects of the COVID-19 vaccines, so that the below percentages do not add up to 83.2%
  7. gCOVID-19: Coronavirus disease of 2019; DMARD: disease-modifying anti-rheumatic drug; HAQ: Health Assessment Questionnaire