Table 2 Comparison of outcomes measures before and after treatment with vitamin B12
Variable | Before treatment | After treatment | Mean diff (95%C.I.) | p value |
|---|---|---|---|---|
FIQR-total score | 49.80 (21.86) | 40.00 (18.36) |  − 9.79 (− 4.13, − 15.45) |  < 0.01 |
FIQR-function domain | 13.17 (7.33) | 10.30 (5.84) |  − 2.86 (− 0.53, − 5.20) | 0.01 |
FIQR-overall domain | 10.32 (6.22) | 8.25 (6.22) |  − 2.07 (− 0.20, − 3.93) | 0.03 |
FIQR-symptom domain | 26.30 (10.39) | 21.44 (8.58) |  − 4.85 (− 1.91, − 7.79) |  < 0.01 |
HADS-anxiety | 9.33 (4.30) | 7.70 (3.60) |  − 1.63 (− 0.35, − 2.90) | 0.01 |
HADS-depression | 6.67 (3.90) | 7.17 (3.76) | 0.50 (1.60, − 0.60) | 0.36 |
SF12-physical component | 33.30 (10.22) | 36.90 (12.30) |  − 3.28 (9.56) | 0.08 |
SF12-mental component | 42.58 (14.70) | 43.82 (14.39) |  − 1.24 (10.15) | 0.94 |
Pain-VAS | 6.01 (2.68) | 5.45 (2.71) |  − 0.58 (− 1.51, 0.35) | 0.21 |