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Table 2 Clinical Features

From: The frequency of Raynaud’s phenomenon, very early diagnosis of systemic sclerosis, and systemic sclerosis in a large Veteran Health Administration database

 

No RP, VEDOSS, or SSc (n = 606,692)

Raynauds Phenomenon

(n = 857)

VEDOSS

(n = 49)

Systemic Sclerosis

(n = 71)

Vasodilator use

92,530 (15%)

410 (48%)

21 (47%)

45 (63%)

Pain

228,045 (38%)

493 (58%)

37 (82%)

46 (65%)

Fecal incontinence

829 (0.1%)

< 1%

< 5%

< 5%

Esophageal Dyskinesia

564 (0.1%)

< 1%

0

< 10%a

Interstitial Lung Disease

11 (0%)

0

0

< 5%a

Pulmonary Arterial Hypertension

542 (0.1%)

< 1%

0

15 (21%)a

Cancer

8736 (1%)

27 (3%)

0

< 5%

High Blood Pressure

120,368 (20%)

222 (26%)a

13 (29%)

33 (47%)a

Diabetes

29,780 (5%)

34 (4%)

< 5%

< 10%

Anxiety

145,477 (24%)

269 (31%)

11 (24%)

21 (30%)

Heart Disease

19,297 (3%)

50 (6%)

< 15%

< 15%

Liver Disease

9740 (2%)

14 (2%)

0

< 10%

Kidney Disease

4545 (1%)

18 (2%)

0

< 5%

Suicidal ideation/attempt

32,050 (5%)

59 (7%)

< 10%

< 10%

Obesity

122,838 (20%)

134 (16%)

< 25%

12 (17%)

Seizures

8821 (2%)

21 (2%)

< 5%

< 5%

Depression

219,302 (36%)

384 (45%)a

22 (49%)a

39 (55%)a

PTSD

257,801 (42%)

394 (46%)

22 (49%)

26 (37%)

  1. adenotes statistical significance across the categories from no conditions, RP, VEDOSS and SSc