Skip to main content
Fig. 1 | BMC Rheumatology

Fig. 1

From: BIOlogical Factors that Limit sustAined Remission in rhEumatoid arthritis (the BIO-FLARE study): protocol for a non-randomised longitudinal cohort study

Fig. 1

RA Aetiopathogenesis. Environmental factors act upon genetic predisposition to cause breach of tolerance (transition A); Unknown factors act on an individual with pre-RA to trigger active RA (transition B); Treatment induces remission (transition C); Unknown factors trigger flare (transition D). Colours denote what is well investigated (green), the focus of the study (orange) and additional processes that this study could inform (pink)

Back to article page