Fig. 3

Difference in DAS28-ESR and -CRP scores at 6 and 12 months after LOT initiation. ACPA: anti-citrullinated protein antibodies; bDMARD: biologic disease modifying antirheumatic drug; CI: confidence interval; CRP: C-reactive protein; DAS: disease activity score; ESR: erythrocyte sedimentation rate; LOT: line of therapy; RF: rheumatoid factor. Note: Where applicable, error bars have been capped from −4 to 1 for presentability