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Table 4 Relationships between meningitis/encephalitis and chondritis in RP patients based on a review of the literaturea

From: Elucidation of predictors of disease progression in patients with relapsing polychondritis at the onset: potential impact on patient monitoring

 

Mean age at onset (y)

Male to female ratio

Time intervalb (months)

Follow-upc (months)

Onset

Last follow-up

AO

RO

MO

AL

RL

BL

All patients (n = 50)

56 ± 1.5d

3.2:1

NAe

13 ± 2.0

34

4

22

41

0

9

Patients presented with meningitis/encephalitis and developed chondritis later (n = 14)

57 ± 3.1

3.7:1

6.2 ± 1.6

8.5 ± 2.1

0

0

3

13

0

1

Patients presented with chondritis and developed meningitis/encephalitis later (n = 17)

58 ± 2.3

7.5:1

12 ± 4.3

18 ± 4.3

16

1

7

14

0

3

Patients presented with both meningitis/encephalitis and chondritis (n = 19)

55 ± 2.4

1.7:1

NA

11 ± 3.5

18

3

12

14

0

5

  1. aA review of the literature was conducted on RP meningitis/encephalitis using PubMed [18, 22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42]
  2. bTime interval (months) between the onset of meningitis/encephalitis and that of chondritis
  3. cFollow-up duration of patients (months)
  4. dAge, time interval, and follow-up duration were expressed as mean ± standard error of the mean
  5. eNA, Not applicable