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Table 2 Enquiry types and motivations to call for DMARDs versus ROC

From: Real-world questions and concerns about disease-modifying antirheumatic drugs (DMARDs): a retrospective analysis of questions to a medicine call center

 

All DMARDs

(n = 1547)

(%)

cDMARD

(n = 1269)

(%)

bDMARDs

(n = 278)

(%)

ROC

(n = 121,709)

(%)

Enquiry type

 Side-effects

25.2†

27.2†

15.1†‡

19.6

 Interaction

19.4†

21.9†

6.5†‡

15.1

 Risk/Benefit & comparison

12.1†

12.5†

9.7‡

8.3

 Mechanism / Profile

9.5†

8.4

15.8†‡

7.0

 Indication & treatment

10.5

10.5

10.8

11.9

 Dose & administration

6.0

6.7

2.5†‡

7.9

 Efficacy

3.1

2.8

5.8†‡

2.8

 Availability

3.0

1.4

11.2†‡

2.6

 Pregnancy & lactation

2.9†

3.1†

1.8†

8.6

 Cost and PBS access

2.0

0.7

8.2†‡

1.4

 Identification / Formulation

1.9

1.2

4.7‡

3.4

 Stability/Storage/Disposal

1.3

0.6

4.7†‡

0.9

 Abuse and withdrawal

1.4

1.5

0.4†

3.4

 Generics

0.4

0.3

0.7

0.8

 Vaccination

0.7

0.7

0.7

1.9

 Outside service brief (e.g.

0.1

0.1

0

1.5

 poisons query)

    

 Non-medicines issue

0.6

0.5

1.1

2.

Motivation to call

 Inadequate information

44.0

44.0

57.7†‡

46.6

 Second opinion

23.6

23.6

18.4†‡

23.5

 Worrying symptom

18.8

18.8

13.4†‡

17.8

 Conflicting information

6.9†

6.9†

1.7†‡

~ 0

 Information overload

2.3

2.3

1.7

1.2

 CMI

0.9

0.9

0.1

0.5

 Forgot information

0.7

0.7

1.3

0.1

 Media

1.2

1.2

3.4†‡

0.9

 Health professionals

0.5

0.5

0.8

6.3

 Other

1.1

1.1

1.7

1.7

  1. PBS Pharmaceutical Benefits Scheme, CMI Consumer Medicines Information
  2. † p < 0.05 versus ROC, with Bonferroni correction
  3. ‡ p < 0.05 versus cDMARDs