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Table 3 Impact of anxiety/depression in patients with RA

From: The multifaceted impact of anxiety and depression on patients with rheumatoid arthritis

 

Overall, N = 1015

No self-reported anxiety/depression, n = 625

Self-reported anxiety/depression, n = 390

P-value (atest)

Clinical measures

 Current flare status, n (%)

  No

860 (86.9)

553 (90.7)

307 (80.8)

 

  Yes

130 (13.1)

57 (9.3)

73 (19.2)

<.001 (FE)

  bMissing, n

25

15

10

 

 DAS28-ESR

  Mean score (SD)

3.6 (1.4)

3.4 (1.3)

4.0 (1.5)

<.001 (MW)

  bMissing, n

348

215

133

 

 Current disease progression, n (%)

  Unstable/deteriorating

167 (16.9)

60 (9.8)

107 (28.2)

 

  Stable

523 (52.8)

339 (55.6)

184 (48.4)

 

 Improving

300 (30.3)

211 (34.6)

89 (23.4)

<.001 (PC)

 bMissing, n

25

15

10

 

Is patient currently in remission?, n (%)

  No

503 (49.6)

269 (43.0)

234 (60.0)

 

  Yes

512 (50.4)

356 (57.0)

156 (40.0)

<.001 (FE)

Employment and impairment

 Patient’s employment status, n (%)

  Unemployed

553 (55.8)

301 (49.1)

252 (66.7)

 

  Employed

438 (44.2)

312 (50.9)

126 (33.3)

<.001 (FE)

  bMissing, n

24

12

12

 

 Percent overall work impairment due to problem (range 0–100)

  Mean (SD)

23.3 (24.4)

18.3 (21.7)

37.5 (26.3)

<.001 (MW)

  bMissing, n

684

380

304

 

 Percent activity impairment due to problem (range 0–100)

  Mean (SD)

33.4 (25.8)

25.0 (22.4)

47.1 (25.1)

<.001 (MW)

  bMissing, n

78

44

34

 

 cRetired/unemployed due to condition, n (%)

  Not due to RA

92 (68.7)

46 (80.7)

46 (59.7)

 

  Due to RA

42 (31.3)

11 (19.3)

31 (40.3)

.014 (FE)

  bMissing, n

881

568

313

 

 Ever changed job due to condition?, n (%)

  No

804 (90.1)

527 (93.4)

277 (84.5)

 

  Yes

88 (9.9)

37 (6.6)

51 (15.5)

<.001 (FE)

  bMissing, n

123

61

62

 

Disability

 HAQ-DI

  mean HAQ-DI score (SD)

0.8 (0.7)

0.6 (0.6)

1.1 (0.7)

<.001 (MW)

  bMissing, n

44

24

20

 
  1. DAS28-ESR disease activity score-28 joint count–erythrocyte sedimentation rate; FE Fisher’s exact test; HAQ-DI Health Assessment Questionnaire Disability Index; MW Mann-Whitney’s U test; PC Pearso n’s chi-squared; RA rheumatoid arthritis; SD, standard deviation
  2. aIndicates statistical test performed
  3. bNumber of patients for whom data were not reported
  4. cFor patients who retired below the retirement age of 65 years. Data available only from patients who initially responded as being retired or unemployed