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Table 5 Proposed Mechanism of Adverse Reactions

From: Adverse infusion reactions to rituximab in systemic lupus erythematosus: a retrospective analysis

 

Immediate Hypersensitivity

Delayed Hypersensitivity

Total

Cycle Number

Unlikely immune mediated

Likely cytokine release

Likely immunoglobulin mediated

Bone pain

Early (24–48 h)

Late (> 48 h)

1

1

2

3

2

1

1

10

2

2

3

1

  

3

9

3

 

2

1

  

1

4

4

       

5

       

6

1

     

1

Total

4

7

5

2

1

5

24

  1. Based on review of the clinical description of the reaction by Clinical Allergist
  2. 4 reactions were excluded from this analysis; 1 death as likely CYC induced ARDS, and 3 due to lack of data
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BMC Rheumatology

ISSN: 2520-1026

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