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Table 1 Demographic and clinical characteristics of the OA phenotypes in MUST

From: Biomarkers of cardiovascular risk across phenotypes of osteoarthritis

 

Number with variable

Hand OA

n = 154

Lower-Limb OA

n = 111

General OA

n = 100

p

Hand vs Lower-limb

p

Lower-limb vs. Gen. OA

p

Hand vs Gen. OA

Age, mean (range)

366

62.1 (42.0–75.0)

62.9 (45.0–75.0)

64.3 (47.0–75.0)

0.40

0.18

0.02

Female gender, n (%)

366

126 (81.3)

62 (55.9)

76 (76.0)

< 0.001

0.002

0.31

Smoking daily, n (%)

363

18 (11.7)

13 (11.9)

12 (12.0)

0.95

0.99

0.94

Higher education, n (%)

359

37 (24.5)

41 (37.3)

26 (26.5)

0.03

0.10

0.72

BMI kg/m2, mean (SD)

356

25.8 (4.3)

28.0 (4.7)

28.1 (4.7)

< 0.001

0.77

< 0.001

CRP mg/L, mean (SD)

364

2.2 (3.5)

2.6 (4.4)

2.9 (3.8)

0.44

0.64

0.17

Use of NSAIDs daily

n (%)

364

27 (17.4)

20 (18.2)

20 (20.2)

0.87

0.71

0.58

Heart rate, beats/min (SD)

258

64.4 (10.4)

63.7 (9.8)

65.4 (10.7)

0.63

0.29

0.56

MHAQ

366

1.20 (1.16–1.25)

1.20 (1.15–1.25)

1.26 (1.19–1.32)

0.98

0.19

0.16

Regular exercise n (%)

365

137 (77.4)

101 (91.0)

87 (87.9)

0.50

0.46

0.90

AIx,% mean (SD

258

32.3 (8.5)

29.0 (8.9)

31.7 (8.6)

0.01

0.05

0.67

PWV m/s, mean (SD)

257

8.65 (2.0)

8.7 (1.9)

9.1 (2.0)

0.61

0.25

0.11

ABI

174

1.2 (0.1)

1.2 (0.1)

1.2 (0.2)

0.02

0.46

0.14

  1. Unadjusted bivariate models. The Chi square, independent samples Student T-test or independent samples
  2. Mann-Whitney U-test were used as appropriate
  3. N number, BMI body mass index, CRP C-reactive protein, NSAIDs non-steroidal anti-inflammatory drugs, AIx augmentation index, PWV pulse wave velocity, BP blood pressure. MUST-OA persons in MUST with osteoarthritis, OCP Oslo community controls, UKPC UK population controls