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Table 5 Sensitivity, specificity, positive predictive value, negative predictive value, positive and negative likelihood ratio in different scenarios of the ASAS axSpA criteria in the diagnosis of axSpA

From: Fatty corner lesions in T1-weighted magnetic resonance imaging as an alternative to sacroiliitis for diagnosis of axial spondyloarthritis

 

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

LR+

LR-

ASAS axSpA criteria (unaltered)

90.3

93.5

90.3

93.5

13.89

0.10

Imaging arm only

84.5

95.2

89.5

95.2

17.60

0.16

Sacroiliitis replaced by ≥3 anterior thoracic FCLs

80.6

93.4

98.0

55.3

12.2

0.21

Sacroiliitis replaced by ≥5 anterior whole spine FCLs

79.4

93.4

97.9

53.8

12.0

0.22

Sacroiliitis or ≥ 3 anterior thoracic FCLs

92.0

93.5

92.0

93.5

14.15

0.09

Sacroiliitis or ≥ 5 anterior whole spine FCLs

91.6

91.9

91.6

91.9

11.31

0.09

  1. PPV positive predictive value, NPV negative predictive value, LR + positive likelihood ratio, LR- negative likelihood ratio, ASAS Assessment of SpondyloArthritis international Society, axSpA axial spondyloarthritis, FCL fatty corner lesion