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Table 2 Association between pre-symptomatic individuals and controls separated by gender in a univariable and multivariable logistic regression analysis

From: Vitamin D in individuals before onset of rheumatoid arthritis - relation to vitamin D binding protein and its associated genetic variants

 

Male

Female

Univariable

Multivariable†

Univariable

Multivariable†

OR (95%CI)

p-value

OR (95%CI)

p-value

OR (95%CI)

p-value

OR (95%CI)

p-value

Total 25(OH) D, (nmol/L)

1.01 (0.99–1.02)

0.451

1 (0.99–1.02)

0.524

0.99 (0.98–1)

0.243

0.99 (0.99–1)

0.184

DBP per 1 mg/L

1.00 (1.00–1.00)

0.310

1.00 (1.00–1.00)

0.631

1.00 (1.00–1.00)

0.433

1.001 (1.000–1.003)

0.034

DBP, per 10 mg/L

0.988 (0.965–1.011)

0.310

0.995 (0.976–1.015)

0.631

1.006 (0.991–1.021)

0.433

1.014 (1.001–1.028)

0.034

Allele A1

0.70 (0.46–1.08)

0.104

0.68 (0.41–1.12)

0.126

1.22 (0.91–1.62)

0.182

1.27 (0.9–1.79)

0.167

  1. 1Allele A frequency in pre-symptomatic males 0.25 and in females 0.28
  2. †Adjusted for BMI, sampling time of year (dark/light), smoking ever, educational level (academic/ no academic), age at the time of sampling
  3. The significant p-values are shown in bold
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BMC Rheumatology

ISSN: 2520-1026

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