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Table 3 Multivariable linear regression analysis for the association between serum uric acid and cardiometabolic function

From: Asymptomatic hyperuricemia and coronary flow reserve in patients with metabolic syndrome

 

Adjusted for

Standardized coefficient (SE)

P-value

All patients (n = 44)

 CFR

Age, sex

0.04 (0.35)

0.92

Age, sex, diabetes, BMI, SSS, Cr

0.07 (0.39)

0.86

Age, sex, diabetes, BMI, SSS, Cr, IL-6, and hs-CRP

−0.12 (0.42)

0.78

 Stress MBF

Age, sex

−0.19 (0.40)

0.63

Age, sex, diabetes, BMI, SSS, Cr

−0.35 (0.44)

0.43

Age, sex, diabetes, BMI, SSS, Cr, IL-6, and hs-CRP

−0.52 (0.47)

0.28

Patients with summed stress score ≤ 3 (n = 28)

 CFR

Age, sex

0.17 (0.43)

0.69

Age, sex, diabetes, BMI, SSS, Cr

0.21 (0.38)

0.60

Age, sex, diabetes, BMI, SSS, Cr, IL-6, and hs-CRP

0.09 (0.43)

0.83

 Stress MBF

Age, sex

−0.13 (0.42)

0.76

Age, sex, diabetes, BMI, SSS, Cr

−0.13 (0.43)

0.76

Age, sex, diabetes, BMI, SSS, Cr, IL-6, and hs-CRP

−0.23 (0.47)

0.63

Patients without diabetes (n = 25)

 HOMA-IR

Age, sex

1.87 (1.30)

0.17

Age, sex, BMI

1.36 (1.26)

0.29

Age, sex, BMI, IL-6 and hs-CRP

2.08 (1.21)

0.10

  1. SE = standard error, CFR = coronary flow reserve, MBF = myocardial blood flow, BMI = body mass index, SSS = summed stress score, Cr = serum creatinine, IL = interleukin, hs-CRP = high sensitivity C-reactive protein, HOMA-IR = Homeostatic Model Assessment of Insulin Resistance